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KPV, the C-terminal tripeptide of alpha-MSH, has been studied as an anti-inflammatory tripeptide that interacts with melanocortin receptors expressed on immune cells and intestinal epithelium

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The peptide reduces renal inflammation and fibrosis while improving endothelial function in kidney vasculature

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Various factors affect melanin production, such as sun exposure, hormonal changes, genetics, and ageing

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