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During treatment, the medication affects appetite regulation, fullness signals and energy balance

These new medications have been described as a major expansion of the treatment landscape beyond current GLP-1based therapies

Since oxidative stress and inflammation play a vital role in pathogenesis and side effects of diabetes, glutamine may help improve the glycemic status and ameliorate side effects of diabetes, due to its antioxidant and anti-inflammatory effects [54]

To understand the biological mechanisms driving these differences, researchers combined human EHR data, mouse behavioral phenomics, single cell RNA sequencing, and rodent behavior and found: GLP-1 receptor expression is higher in key brain regions associated with nausea in females

10.2337/dc07-0841 176 LiaoJ.WangJ.JiaS.CaiZ.LiuH

Biomed Sci