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Three of the sequences are very similar to each other (~96% sequence identity) and may represent transcripts derived from different homeologous alleles of the same gene (Figure S4)

In addition, 4-HNE has a role in numerous cell processes, including but not limited to oxidative stress [66], inflammation [67], cell proliferation [68] and cell death [69]

Biochem Pharmacol (2014) 88:54859

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2009 RCT documented improvements in mottled hyperpigmentation alongside fine-wrinkle reduction in photoaged skin 10