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People with obesity consume more food than is needed to maintain an ideal body weight, despite the discrimination that accompanies being overweight and the wealth of available information that overconsumption is detrimental to health

Early Research in Autoimmune Disease & Fibromyalgia What It Shows and Why Its Limited Fibromyalgia: Early Signals, No Conclusions Some observational reports describe symptom improvements (pain, fatigue, opioid use) in people taking GLP-1 medications, but limitations are consistent: non-randomized design, small samples, and confounding from weight loss, sleep, and metabolic improvements

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As previously reported 20 , DIO wild-type mice fed on the high-fat diet displayed impaired glucose tolerance (Fig