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Constantinos Glynos said: The observed detrimental effects in the lung upon e-cigarette vapor exposure in animal models highlight the need for further investigation of safety and toxicity of these rapidly expanding devices worldwide. The researchers conducted their experiment by exposing different groups of mice to cigarette smoke, various e-cig vapors or clean air four times each day, with every session separated by 30-minute smoke-free intervals

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We also used these regressions to examine whether a quadratic trend might be better than a linear trend but found no evidence of this (the quadratic coefficients were negligible and not statistically significant)

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