Histone acetylation and depression The first evidence of histone acetylations role in depression came from studies showing that HDAC inhibitors (HDACi), used alone or with antidepressants, enhanced antidepressant responses in animal models 139,140,141
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A mutant impaired in the major high-affinity sulfate transporter SULTR1;2 responsible for uptake in Arabidopsis roots was reported earlier to contain decreased amounts of glutathione 83 but our data indicate that sultr1;2 seedlings exposed to AITC have a WT-like response
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2025 Aug 26;68(Suppl 1):S982