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Lastly, BPC 157 counteracts tumor cachexia, muscle wasting, and increases in pro-inflammatory/procachectic cytokines, such as interleukin-6 and tumor necrosis factor-, and significantly corrects deranged muscle proliferation and myogenesis through changes in the expression of FoxO3a, p-AKT, p-mTOR, and p-GSK-3 (mitigating cancer cachexia)

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The anti-inflammatory and antioxidant effects of GLP-1RAs observed in other organ systems may prevent damage in ocular tissues, leading to reduced risk of nonexudative age-related macular degeneration (AMD), exudative AMD, and primary open-angle glaucoma (POAG) compared to other diabetic medications (Figure 1)

In the body, thioctic acid activates a protein that binds to glutathione and works as an antioxidant