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During intense exercise, your body experiences increased metabolic demands that vitamin B12 helps address through multiple pathways

A word on why once daily is the anchoring frequency rather than something more elaborate

That said, the compound has not been through full Phase III trials or FDA drug approval

The better option depends on your treatment goal, comfort level, safety needs, and provider recommendation

Questions remaining include optimal human dosing, long-term safety, effects across different populations, interactions with diet and exercise, and whether benefits extend beyond weight loss to improvements in cardiometabolic disease outcomes

There are four different kinds of B12, some of which are more bioavailable and active than others