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Meissner HO, Mscisz A, Reich-Bilinska H, et al
These autoantibodies against immunomodulatory proteins (including cytokines, chemokines, complement components and cell-surface proteins) could attack tissues of patients, thereby impair host cell signals, perturb immune function, damage organ systems, and increase COVID-19 severity 36
Patients present at more advanced stages with greater Breslow depth, higher ulceration rates, and more aggressive tumor behavior