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The peptide backbone is engineered from a GIP sequence, modified to achieve balanced activation across all three target receptors

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Furthermore, phosphorylation of ACC and AMPK, which indicates activity of AMPK, was significantly enhanced by the administration of MG and AICAR, but this phosphorylation was partially suppressed by GLP-1 (Fig

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[DOI] [PubMed] [Google Scholar] [125].Medina JH, Viola H, ERK1/2: A key cellular component for the formation, retrieval, reconsolidation and persistence of memory