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Eprenetapopt/APR-246/PRIMA-1 MET is a small molecule drug which has been proposed to bind to cystine residues in mutant p53, thermodynamically stabilizing it such that both WT conformation and functionality is restored [9]

The drugs are activating that system differently

If your provider determines that treatment is appropriate, you will receive a personalized care plan

H., Kramer, M

"Transcriptional switch by activating transcription factor 2-derived peptide sensitizes melanoma cells to apoptosis and inhibits their tumorigenicity"

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