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Glucagon-like peptide-1 (GLP-1) receptor agonists mimic (copy) the GLP-1 hormone that is naturally released in your gastrointestinal (GI) tract in response to food

You might experience the following symptoms: Nausea or an upset stomach Diarrhea or loose stools Vomiting in some cases Constipation or bloating Reflux or heartburn These symptoms often happen when the dose increases

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Another way through which the increased astrocyte glutamate uptake during DR can contribute to increasing cytoplasmic NADPH generation and the [NADPH]/[NADP + ] is through increasing the rate of glutaminolysis (Figure 2E)