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This article compares the two the way the published evidence actually supports, which is more sobering than the marketing
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325 GIPR is downregulated in adipose tissue during insulin-resistant states, such as obesity, and several studies suggest that GIP augments insulin actions in adipose tissue
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These are typically intramuscular injections starting with high doses weekly, then switching to monthly 1,000 mcg doses for the rest of a patients life (No Stomach for Cancer, 2023)
In the STEP 1 clinical trial for semaglutide, participants regained up to two-thirds of the weight they had lost within a year of stopping the medication
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