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The FDA has now recommended a prospective, randomized, blinded trial of setmelanotide for acquired HO over a 12-month treatment period ( following early phase 2 trial indications that this drug may be clinically effective in weight reduction [70, 71]

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Further studies are needed to investigate the possibility of late-onset pancreatitis as a side effect of semaglutide

35 Weight loss The Framingham Heart Study reported that for every unit increase in body mass index (BMI) there is an associated 5-7% increased risk of HF

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Nausea: This can be managed by avoiding strong smells and eating crackers, mint, or ginger-based food or drinks about a half hour after taking a GLP-1 drug