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Prevalence of Dercum Disease Many women with lipedema have been miscategorized as having Dercum disease when actually they have lipedema and metabolic syndrome, making the prevalence estimate of 1/1000 for Dercum disease in Sweden too high (223)

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In contrast to the replenishment of GSH precursors, System Xc- activators primarily enhance the expression of SLC7A11 to promote the uptake of cystine, which is both a specific substrate and a direct activator of the system (137)

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