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This route achieves tissue concentrations 10-20 times higher than topicals, making it the preferred method for researchers seeking maximum effect
This peptide is frequently investigated for its involvement in IGF-1 receptor activation, protein-synthesis signalling, cellular proliferation pathways, and metabolic-response research
Warburg revisited: regulation of mitochondrial metabolism by voltage-dependent anion channels in cancer cells
"Photobiomodulation: the mechanism of action." BME Frontiers , 2016, 1-15
Thus were the conclusions made in a 2015 paper published in Cell Metabolism , in which the authors noted that MOTS-c has physiological similarities to the first-line diabetes drug metformin with regard to managing glucose utilization, metabolism, and body weight.18 Reduced body fat Considering the effects that MOTS-c has on insulin response and glucose uptake two factors associated with weight gain the authors of the 2015 paper referenced above also examined the peptides potential for preventing obesity.19 Specifically, in a group of mice fed a high-fat diet, MOTS-c appeared to prevent obesity onset.18 Other studies have corroborated these results by finding that higher plasma MOTS-c levels are negatively correlated with obesity.20 Improved physical performance Recall that endogenous MOTS-c can be activated by exercise, allowing your skeletal muscles to use glucose for energy to meet their high energy demand
