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On the other hand, Semaglutide works through a single pathway, focusing only on GLP-1 receptors
The difference is not always genetic
Hypoglycaemia risk When used as monotherapy, GLP-1 receptor agonists carry minimal hypoglycaemia risk due to their glucose-dependent mechanism
Patients receiving liraglutide injection in combination with an insulin secretagogue (e.g., sulfonylurea) or insulin may have an increased risk of hypoglycemia, including severe hypoglycemia
Therefore, there are limited clinical trial data with semaglutide use in pregnant women. Animal studies have suggested semaglutide can cause foetal abnormalities
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