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9,11 Early reports of pancreatitis in animal studies with the use of sitagliptin, clinical reports of humans treated with exenatide and demonstrations of preneoplastic pancreatic ductal lesions in animals treated with GLP-1 receptor agonists led to concerns about the pancreatic safety of GLP-1 receptor agonists

nonetheless, I ask patients to tell proceduralists and anesthesiologists that they are on a GLP-1 and to follow any fasting instructions provided

Dose escalation can be delayed by 4 weeks if adverse effects persist, and treatment is not recommended for patients with severe gastrointestinal disease

There is also a practical advantage

This is where my mindset really came into play

Biochimie (2019) 159:2335