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In the UK: Ipamorelin and CJC-1295 are unlicensed for human consumption

It should further be noted that there are examples of digital private clinics with a niche for weight-loss treatment that started in 2021 [71], and these most probably affected the rise of GLP-1 RAs observed after 2021

Red flags in constipation [6] [13] [14] [15] These features in a patient with constipation should prompt evaluation, e.g., with a diagnostic colonoscopy, for an underlying colorectal malignancy

Ataxia with vitamin E deficiency