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4A), indicating the potential of these conjugates to serve as relevant clinical markers when blood samples are available, as it is in the case of acute intoxication, to monitor the elimination of the toxic NAPQI

This effect was reversed by deletion of NOX1-4, NOX3 alone, or treatment with the ROS scavenger N-acetyl cysteine (NAC)

Orouji E, Raman AT, Singh AK, Sorokin A, Arslan E, Ghosh AK, Schulz J, Terranova C, Jiang S, Tang M, Maitituoheti M, Callahan SC, Barrodia P, Tomczak K, Jiang Y, Jiang Z, Davis JS, Ghosh S, Lee HM, Reyes-Uribe L, Chang K, Liu Y, Chen H, Azhdarinia A, Morris J, Vilar E, Carmon KS, Kopetz SE , Rai K

Achenbach and Rescorla 2000) it was completed by the child's caregiver

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