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In vivo studies have shown that VEGF enhances vascularization and reduces retrograde degeneration of corticospinal tract axons and thus stimulates axon regeneration in the injured brain area (Conforti et al

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In fibroblast-centric models, readouts consistent with collagen and matrix component regulation have been reported, supporting the use of GHK-Cu as a laboratory tool in matrix biology research

Hierarchy of Evidence: Level A (Human meta-analyses and systematic reviews of CNS drug delivery)