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notes that a significant number of people who are B12 deficient are unable to absorb the vitamin from food or supplements, and so need to inject it, which they can only do at their GP practice

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When comparisons were made, all relevant treatment groups were included

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Patients experiencing severe abdominal pain, persistent vomiting, signs of infection, or allergic reactions should seek urgent medical attention

There is a theoretical case for using both in certain patients, targeting different physiological mechanisms simultaneously, though this approach is under evaluation and not yet standard of care