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A coffee enema is an alternative colon cleanse where a coffee and water mixture is introduced into the colon to help detoxify the body, remove impurities, and support digestive health

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Chauhan, A., et al., Oxidative stress in autism: increased lipid peroxidation and reduced serum levels of ceruloplasmin and transferrin the antioxidant proteins

[1] You may know it by its research name, PT-141, which is still commonly used in wellness and peptide medicine settings