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doi: 10.3390/MOLECULES23061368 17 LammiCZanoniCArnoldiAVistoliG

Brendon Stubbs is part funded by the NIHR Biomedical Research Centre at South London and Maudsley NHS Foundation Trust

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Findings come from preclinical models only and remain limited

Dosing The starting dose for adults is generally low, to minimize gastrointestinal side effects, and is gradually escalated based on individual tolerance and response to treatment

Statistical analysis Sample size calculation was done by considering the results of a recent study [] , with a study power of 80% and, a confidence interval of 95% based on the following formula