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*Correspondence: Alina German, [email protected] Deceased ORCID: Alina German, orcid.org/0000-0003-0934-9420

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PMID: 18728176 Messenger AG, McKillop J, Farrant P, McDonagh AJ, Sladden M

[2] This side effect typically emerges during dose initiation or escalation and often diminishes over several weeks as physiological adaptation occurs