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Any microdosing should be done under supervision with your provider and appropriate lab work, says DeGore

Practical Steps to Manage Appetite If you are skipping a dose due to the five-day rule, you may feel hungrier toward the end of the week

An Uncharted Frontier: Microdosing and the FDA The FDA does not currently have guidelines on microdosing GLP-1 medications, and its clear that more study is needed to understand the risks, benefits, and efficacy of doses that are lower than those recommended by current prescription guidelines

But, and this matters, those averages include people at both extremes

Bloodwork and additional testing may also be done to see if the patient is already a diabetic or prediabetic

The medication contains a GLP-1 receptor that mimics the hormone the body produces when food is in the intestinal system to suppress hunger pangs and the desire to eat voraciously