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All of our regimens will provide a physiologically negligible amount of cyanide well below the EFSAs acute reference dose safety threshold of 20 g/kg of body weight (1,270 g for a 140 lb (63.5 kg) person) per day

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Thirdly, it is well known that CYPs generate ROS while metabolizing a wide range of substrates via coupling and auto oxidation reactions 55 , and our results are in agreement with previous reports 22,56 showing that acute treatment of BaP (1 M) in U1 cells for 3 days increase the ROS levels