However, in view of the excellent safety profile of B12, even at high doses, supplementation, ideally as part of a more comprehensive nutritional programme, may still be of value when the clinical picture and/or other factors (e.g
Selected Bibliography Lin, C
SSRIs, SNRIs, MAOIs, TCAs are hard contraindications even at low topical concentrations.
Li et al., 2007, 2011)
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Dosing is once daily, subcutaneously, with the timing chosen to align with natural lipolytic windows, typically before bed (to coincide with overnight fasting and growth hormone pulses) or first thing in the morning before training and food