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Inform patients using these concomitant medications of the risk of hypoglycemia and educate them on the signs and symptoms of hypoglycemia Acute Kidney Injury Due to Volume Depletion: There have been postmarketing reports of acute kidney injury, in some cases requiring hemodialysis, in patients treated with semaglutide

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Higher therapeutic doses require a more concentrated formulation or multiple injections per session

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These aggregates reduce the amount of active, available semaglutide in solution

Assuming things go to plan, semaglutide is likely to have an extended shelf life as a top-tier obesity and diabetes treatment for Novo Nordisk, even with other companies fast approaching with their own drug candidates on the way