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Conclusions Within this specific population, GLP-1 RAs exhibit significant reductions in BW, BMI, WC, and SBP

Return expired or unused medication to a pharmacy take-back site or follow local regulations

Heavy metals are elements that can be toxic and very dangerous even in low concentrations

Weight regain of 10-15% or more from the lowest post-operative weight, or failure to achieve adequate excess weight loss, may prompt consideration of pharmacological intervention

Adjust injection timing (if needed): Some patients find the timing of their GLP-1 dose can influence side effects

One study noted that ghrelin may upregulate cartilage-specific genes, and another noted that ghrelin may help mesenchymal stem cells (universal stem cells that can differentiate based on need) to target cartilage repair [9, 10]