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Analysis of the Injured Area with Special Histochemical Sirius Red Staining Collagen proliferation on Sirius red staining was significantly increased in the treated animals compared to the controls at all three time intervals, 1, 2, and 3 weeks after injury (Figure 19 and Figure 20)

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The rationale: early-phase neuroplasticity benefits from sustained HGF/c-Met signaling, but once synaptic remodeling is initiated, daily pulses are sufficient to maintain the effect