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Poor blood sugar control and obesity are closely linked in a cycle where each can contribute to the other: high blood sugar caused by insulin resistance results in excess production of insulin, which in turn encourages the body to store fat, while obesity worsens insulin resistance

Direct answer: Yes, rapid weight loss linked to Semaglutide can increase the risk of gallstones

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Danish investigators compared GLP-1 receptor agonists with DPP-4 inhibitors, the US analysis compared semaglutide with other anti-obesity medications, and the Swedish study examined medication periods within a population already diagnosed with alcohol use disorder

Shared decision making Overweight and obesity management (NG246)

"These patients are experiencing, maybe for the first time in their life, back pain," Dohring said