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It mimics the activity of HGF a protein involved in cellular growth, survival, and repair and binds to c-Met receptors present on neurons

Demeestere I, Gervy C, Centner J, Devreker F, Englert Y, Delbaere A: Effect of insulin-like growth factor-I during preantral follicular culture on steroidogenesis, in vitro oocyte maturation, and embryo development in mice

Despite the same mode of action, the different gliptins diverge in their pharmacodynamic and pharmacokinetic properties, which might be clinically relevant for some patients (9, 96)

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doi: 10.1111/ bju.12363

Immunoblot To measure Akt phosphorylation, confluent bFLS were treated with bTNF- for 5 min at 37 C under 5% CO 2