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This dual action decreases pyroptotic cell death, ultimately mitigating dopaminergic neuron loss and improving motor dysfunction in PD rats (60)

173,174 PROM2 overexpression is strongly associated with the increased metastatic potential of melanoma, with similar results found in patient-derived xenotransplantation models of RCC and TNBC

[DOI] [PubMed] [PMC] Waller KJ, Saihi H, Li W, Brindley JH, De Jong A, Syn WK, et al

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[17] [22] Bromantane may activate intracellular signaling cascades by some mechanism (e.g., agonizing some as-yet-undetermined receptor) to in turn activate protein kinases, which in turn cause increased transcription of TH and AAAD

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