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The fact that the double-cysteine mutations only partially abolish the physiological function may imply that not all the expressed mutants have an intact disulfide bridge and that the observed conformation is only one possible inactive state on the cell surface, as supported by the EM data and MD simulations below

The percentage rose to 50 percent among obese men with diabetes

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(February 1968)

the salutary effect of NaBPC157 consistently appeared after only two weeks of medication and it was clearly evident after one year of application

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