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Tant, L., Gillard, B., & Appelboom, T

The buildup of excess fluid in the body's tissues is a result of water retention, fluid retention, or edema

Contrary to alternative method based on a competitive hypothesis, GSVA is based on self-contained null hypothesis which analyzes each gene set in isolation, assessing differential expression of the gene set without comparing to a background [62, 63]

J Clin Invest 111:785793 Dvila D, Torres-Aleman I (2008) Neuronal death by oxidative stress involves activation of FOXO3 through a two-arm pathway that activates stress kinases and attenuates insulin-like growth factor I signaling

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