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Consult a health care practitioner prior to use if you have liver or kidney disease, have been instructed to follow a low protein diet, if symptoms persist or worsen or for use beyond 6 months

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Short term, spikes cause symptoms like fatigue and headaches

In animal research, giving Akkermansia to mice improved features of diet-induced metabolic problems (Everard et al., 2013), and a small human trial found that pasteurized Akkermansia was safe, well tolerated, and linked to some improved metabolic markers in adults with overweight or obesity (Depommier et al., 2019)