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Modified atmospheric packaging, characterized by higher CO and lower O levels compared to air, has been found to reduce respiration rates, ethylene production, sensitivity, microbial spoilage, and induce changes in physiological and biochemical processes

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The approach combines hypotonicity and thermosensitive gel-forming polymers (e.g., Pluronic F127) formulated below their critical gel concentration (CGC), allowing for rapid and uniform water absorption-driven spreading over the ocular surface