As a biguanide antihyperglycemic agent, metformin works primarily by decreasing hepatic glucose production, reducing intestinal glucose absorption, and improving insulin sensitivity in peripheral tissues
B12 (cobalamin) is a water-soluble vitamin essential for neurological function, red blood cell formation, and DNA synthesis Joint pain is not listed as a recognised adverse effect in the BNF or licensed B12 product information When joint discomfort occurs after starting B12, it is typically coincidental or related to excipients, injection technique, or pre-existing conditions Severe B12 deficiency itself can cause neuropathic symptoms that may be misinterpreted as joint pain Do not discontinue prescribed B12 treatment without medical guidance, particularly for confirmed deficiency or pernicious anaemia Seek prompt medical advice for severe joint pain, hot swollen joints with fever, or symptoms of allergic reaction Table of Contents Can Vitamin B12 Cause Joint Pain
This whole circus leaves many patients with recurring, irreparable symptoms
And it's given us a new thing to worry because we never had sleep problems our entire life
This stated that patients should undergo a telephone interview with their healthcare provider on the day of their appointment for their injection
Safety Information Research compound - safety profile varies by context