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However, recent large cohort studies have not supported an increased risk of suicidality compared to other diabetes medications

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The study maintained blinding for active versus placebo treatment

221 Dual receptor agonists targeting GLP-1 and GIP, such as tirzepatide, have also exhibited promising efficacy in diabetes management, notably in terms of weight reduction and glycemic control

Regulatory submissions will depend entirely on the final compilation of the TRIUMPH safety dossiers, meaning widespread commercial availability remains a future milestone

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