The landscape of heart failure (HF) management is evolving alongside a deeper understanding of how metabolic dysfunction drives cardiac pathology and the progression of HF, particularly in phenotypes like HF with preserved ejection fraction (HFpEF) associated with obesity
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But this timeline is not carved in stone
GLP-1 agonists/analogues show beneficial effects on most of the multiple alterations underlying MASLD and cirrhosis progression [10]
Tirzepatide is a related medication that works on both GLP-1 and GIP receptors and requires similar monitoring
The timing logic changes entirely