The current evidence base points to several overlapping molecular pathways operating in parallel: VEGFR2/Akt/eNOS Angiogenic Signalling A primary mechanistic axis involves upregulation of vascular endothelial growth factor receptor 2 (VEGFR2), leading to activation of the Akt/eNOS (endothelial nitric oxide synthase) downstream pathway
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Obesity is a well-established risk factor for numerous cancers, including colorectal, pancreatic, liver, uterine, ovarian, and breast cancers, Bilchik detailed
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Studying and describing the exact mechanisms of obesity development allows modern medical science not only to understand the essence of this phenomenon but also to develop clinically effective medical therapy aimed at correcting this deviation
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