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Participants using semaglutide lost an average of 15-18% of body weight, with many achieving results at lower doses that could be continued indefinitely

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doi:10.1038/s41598-020-72887-7

Animal experiments Animal experiments were performed using hemizygous or homozygous human FcRn Tg32 mice (B6.Cg- Fcgrt tm1Dcr Tg(FCGRT)32Dcr/DcrJ, The Jackson Laboratory)