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Its used for type 2 diabetes and has a recently approved cardiovascular label extension, and one oral semaglutide product in development for obesity and cardiovascular risk reduction

Total RNA was isolated using commercially available Bead-Beat Total RNA Mini Kit (A&A Biotechnology, Gdansk, Poland) according to the manufacturers instructions

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Other companies, including Terns Pharmaceuticals (TERN-601), Structure Therapeutics (GSBR-1290), and Viking Therapeutics, have oral GLP-1 programs at earlier stages of development, but none has reached Phase 3 or generated the depth of clinical data available for orforglipron