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It also plays a role in immune function and mood regulation

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Using a lower dose of medication will slow weight loss, but it may cause fewer cosmetic side effects

10.1182/blood-2013-06-505792 43 CostaE.RochaS.Rocha-PereiraP.NascimentoH.CastroE.MirandaV.et al (2008)

Slow escalation significantly reduces early gastrointestinal symptoms and increases the likelihood of sustained therapy