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In vivo and in vitro studies on nicotine exposure demonstrated the activation of several downstream signaling pathways in fibroblast and airway epithelial cells [80, 81]

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Some cities also restrict the content of tobacco-related signage near schools

Recently, a study that utilized the PNE ADHD mouse model found that administration of MPH (1 mg/kg) restored the behavioral impairments and neuroplasticity changes in the AMPAR subunit composition and distribution while restoring the density and maturation of dendritic spines of the hippocampal pyramidal neurons (Figure 3) [83]