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In addition, the released lactate can bind to the hydroxycarboxylic acid 1, HCA1 (encoded by the HCAR1 gene) receptor triggering autocrine effects in the adipocyte or paracrine effects in other cells

Although the behavioral effects were relatively mild, D1 overexpression and its subsequent termination in mPFC also correlated with increased IL-6 in the hippocampus, linking the modulation of D1 expression to neuroinflammation

Life Sci 237:116893 Obara-Michlewska M, Szeliga M (2020) Targeting glutamine addiction in gliomas

Heavy metal pollution and male fertility: An overview on adverse biological effects and socio-economic implications

ISRN Endocrinol

Data of the phase 1b multiple ascending dose (MAD) trial was presented (click here to find the presentation) at the Obesity Week (Obesity Society), November 3-6, 2023 in San Antonio, Texas