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Potential Development of Chronic and Degenerative Diseases A chronic deficiency in glutathione can contribute to the development or worsening of various health conditions like: Neurological Disorders: Low glutathione levels are associated with conditions like Parkinsons and Alzheimers where oxidative stress and impaired detoxification may play a role in the progression of neurodegeneration

Moreau and King, 2012)

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A meta-analysis of 8 RCTs found that NAC supplementation significantly reduced fasting glucose (WMD: -5.84 mg/dL) and HbA1c (WMD: -0.27%) in people with metabolic conditions (Sarkaki et al., Clin Nutr ESPEN, 2021) [57]

Alternatively, if the acidosis fails to respond to N-acetylcysteine, this indicates the need to search further for alternative diagnoses

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