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its a critical safety net

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Conclusion This study confirmed that trophoblast ferroptosis occurs in the pathological state of PE and that trophoblast are specifically sensitive to ferroptosis

We also note that the flux around the methionine cycle is 205 M/hr and approximately half enters the transsulfuration pathway (V CBS = 103 M/hr) and half is remethylated to methionine in accordance with the results of Finkelstein and Martin [22]

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