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Cellular and humoral immune responses to adenovirus and p53 protein antigens in patients following intratumoral injection of an adenovirus vector expressing wild-type

The progressive ramp through the cycle is intentional: it allows the body to respond to the compound gradually, lets the provider assess tolerance and response before increasing the dose, and avoids the unnecessary load of starting at maximum dosing when the tissue is still in early repair phases

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3H, J, K), indicating enhanced cystine transport and antioxidant capacity [30]

In this way, SIRTs and PGC-1 are between the principals redox hubs in the cells (Fig

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